Seagen
Research Associate II Protein Design
Research - Bothell, Washington
Description
Seagen is a global, multi-product biotechnology company dedicated to developing and commercializing transformative cancer medicines. As the industry leader in antibody-drug conjugate (ADC) technology, we pioneered a new generation in the science of harnessing antibodies to deliver cell-killing agents directly to cancer cells. Seagen’s dedication to improving the lives of cancer patients goes beyond science, and we believe that every employee has a role in contributing to this mission. By working together with a shared dedication and diverse perspectives, we are able to reach our full potential and make a real difference in the world. Seagen is a fast-growing company and has an abundance of opportunities available for you to grow your career. Put your passion to work at Seagen and join us!
Summary
We have an exciting opportunity for a highly motivated, organized, and creative protein biochemist to participate in advancing our antibody-drug conjugate (ADC) technology in the Protein Engineering group in Discovery Research at Seagen. We seek an individual with excellent interpersonal and scientific skills who will enjoy working at the bench in a collaborative fashion alongside scientists with a variety of backgrounds and specialties.
Principal Responsibilities:
- Prepare antibodies and ADCs using established and experimental expression, purification, and bioconjugation methodologies
- Characterize antibodies and ADCs using analytical techniques (HPLC, mass spectrometry) and binding assays (flow cytometry, ELISA, BLI)
- Culture mammalian cells and use for cell-based assays
- Design and implement novel antibody engineering strategies to advance ADC technology
- Work collaboratively with other scientists and departments on research projects
- Record and communicate scientific results, including giving presentations at project and departmental meetings
Required Qualifications:
- B.S. or M.S. degree in biochemistry or a related field, with 2+ years of research experience
- Significant experience in protein chemistry, protein expression and purification, cell-based assay development, and/or analytical biochemistry
- A track record of generating reproducible and reliable results with limited supervision, yet understands when to seek input and when to make independent judgments
- Proven creativity, problem-solving, and written/oral communication skills
- Self-motivation to understand the principles of therapeutic protein biology
- Eagerness to work in a fast-paced, flexible, and collaborative team environment
Preferred Qualifications:
- Experience with mammalian cell culture
- Experience with antibody binding assays and analyses including FACS, ELISA, SPR and/or BLI
As the leading employer in our industry in the Pacific Northwest, Seagen is proud to offer a competitive total compensation package as well as a comprehensive benefits program designed to support the whole lives of our employees and their families. Benefits include medical, vision and dental coverage, group and supplemental life insurance, 401(k) with company match, tuition reimbursement, relocation assistance and much more. To learn more about Seagen, visit www.seagen.com.
Seagen is an equal opportunity employer. All qualified applications will receive consideration for employment without regard to race, age, gender identity, sexual orientation, color, religion, sex, marital status, national origin, protected veteran status, disability status, or any other status protected by federal, state, or local law.
To prevent the spread of COVID-19, and as an integral part of its public health and safety measures, Seagen requires that all newly-hired employees be fully vaccinated against COVID-19 before commencing employment, subject to reasonable accommodation and other requirements of applicable federal, state, and local law.
Apply:
Seagen
Seagen is an Equal Opportunity Employer
Submitted: 04/01/2022
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